Cpn10 Antibody: FITC

SKU: orb152101

Description

Rabbit polyclonal to Cpn10 (FITC). Chaperonin 10, otherwise known as Cpn10, (groES in E. coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (Hsp10s). Cpn10 acts as a co-chaperone and interacts with the Hsp60 family to promote proper folding of polypeptides. Cpn10 and Cpn60 both exhibit sevenfold axis of symmetry and function as a team in the protein folding and assembly process. Cpn10 has been located in human platelets, but is also present in human maternal serum. It has been reported that human Cpn10 is identical with early pregnancy factor, which is involved in control over cell growth and development. This identification suggest that Cpn10 may act like a hormone in stressful situations such as pregnancy..

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Cancer,Epigenetics,Cancer | Heat Shock | Cell Signaling | Protein Trafficking | Chaperone Proteins | Cell Signaling | Metabolism | Mitochondrial Metabolism | Mitochondrial Markers

Images & Validation

• Tested Applications: ICC, IF, IHC
• Dilution Range: WB (1:1000), IHC (1:100)
• Reactivity: Bovine, Canine, Frog, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep
• Application Notes:
  1 µg/ml of SPC-193 was sufficient for detection of Cpn10 in 10 µg of Hela lysates by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Human Cpn10 peptide AA 91-101
• Target: Cpn10
• Molecular Weight: 10kDa
• Conjugation: FITC

Storage & Handling

• Storage: Conjugated antibodies should be stored according to the product label
• Buffer/Preservatives: 640.91mM DMSO, 136.36mM Ethanolamine, and 9.09mM Sodium Bicarbonate in 90.9% PBS
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

10kDa Chaperonin antibody, Chaperonin 10 antibody, Cpn 10 antibody, EPF antibody, GROES antibody, Heat Shock 10kD protein1 antibody, HSP10 antibody, HSPE1 antibody

Quick Database Links

Gene Symbol

Cpn10

UniProt

P61604

NCBI Gene ID

3336

RefSeq (Protein):NP_002148.1