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CT-1 Protein, Human, Recombinant (His)

SKU: orb1962130

Description

Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF-κB DNA -binding activities.

Research Area

,Recombinant-Protein

Images & Validation

Key Properties

Expression SystemE. coli
Biological OriginHuman
Biological ActivityCardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF-κB DNA -binding activities.
TagN-6xHis
Expression RegionMet1-Ala201
MW25 KDa (reducing condition)
Purity98.00%
Protein SequenceMet1-Ala201

Storage & Handling

Storage-20°C
Expiration Date6 months from date of receipt.
DisclaimerFor research use only

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UniProt Details

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Protocol Information

Protein Handling and Storage Guide
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10 μg
$ 290.00
50 μg
$ 650.00
500 μg
$ 2,170.00
1 mg
$ 3,070.00
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