Cyclin D1 (G1-Cyclin & Mantle Cell Marker) Antibody

SKU: orb607673

Description

Mouse monoclonal antibody against Cyclin D1 (G1-Cyclin & Mantle Cell Marker) conjugated to PE

Research Area

Product Categories/Products/Antibodies/Primary Antibodies,Cancer,Cancer/DNA Damage,Product Categories/Antibodies,Product Categories/Products/Antibodies,Epigenetics,AKT Signaling|Bladder Cancer|Breast Cancer|Cancer|Cardiovascular|Colon Cancer|Cytokine Signaling|Immunology|Infectious Disease|Lung Cancer|Nuclear Marker|Signal Transduction|Transcription Factors

Images & Validation

• Tested Applications: FC, IF, IHC, WB
• Dilution Range: Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood);Immunofluorescence (1:50-1:100 for 30 minutes at RT)Optimal dilution for a specific application should be determined.
• Reactivity: Human
• Application Notes:
  Positive Control: T47D, ZR75, BT474, SKBR3, MCF-7, MDA-MB-453, HT29, Ramos, Jurkat or A431 cells. ~60% of mantle cell lymphomas and ~40% of breast carcinomas are positive.

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2a
• Clone No.: DCS-6
• Immunogen: Human full length recombinant cyclin D1 protein
• Target: CCND1
• Source/Expression System: Bioreactor
• Molecular Weight: 36kDa
• Conjugation: Unconjugated

Storage & Handling

• Storage: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Form/Appearance: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Buffer/Preservatives: Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules. Prepared in 10mM PBS with 0.05% rAlbumin and 0.05% azide. Contact us if you require this Ab in a different format.
• Concentration: Purified Ab conjugated to PE
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

B cell CLL/lymphoma 1, B cell leukemia 1, B-cell lymphoma 1 protein, BCL-1 oncogene, CCND1 protein, CCND1/FSTL3 fusion gene, CCND1/IGHG1 fusion gene CCND1/IGLC1 fusion gene, CCND1/PTH fusion gene, cD1, Cyl 1, G1/S-specific cyclin-D1, Parathyroid adenomatosis 1, PRAD1 oncogene

Quick Database Links

Gene Symbol

CCND1

UniProt

P24385

NCBI Gene ID

595