CYP11A1 Rabbit Polyclonal Antibody

SKU: orb156513

Description

CYP11A1 Rabbit Polyclonal Antibody

Research Area

Cholesterol Metabolism, Metabolism, Hormone Biosynthesis, Hormone Research, Lipid Metabolism, Cell Biology, Lipids and Lipoproteins Metabolism, Metabolism, Metabolism

Images & Validation

• Tested Applications: WB
• Dilution Range: WB=1:500-5000
• Reactivity: Rat
• Predicted Reactivity: Bovine, Canine, Equine, Porcine, Rabbit, Sheep

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human CYP11A1/P450SCC (41-140/521aa)
• Target: CYP11A1
• Molecular Weight: 53/57 kDa
• Purification: affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cholesterol 20 22 desmolase; Cholesterol desmolase; Cholesterol monooxygenase(side chain cleaving); Cholesterol side chain cleavage enzyme; Cholesterol side chain cleavage enzyme mitochondrial; Cholesterol side-chain cleavage enzyme; CP11A_HUMAN; CYP11A; CYPXIA1; Cytochrome P450 11A1; Cytochrome P450 11A1 mitochondrial; Cytochrome P450 family 11 subfamily A polypeptide 1; Cytochrome P450 subfamily XIA; Cytochrome P450(scc); Cytochrome P450C11A1; mitochondrial; P450SCC; Steroid 20 22 lyase

Quick Database Links

Gene Symbol

CYP11A1

UniProt

P05108

Dong, Yixin et al. EPC1/TIP60-Mediated Histone Acetylation Facilitates Spermiogenesis in Mice Mol Cell Biol, 37, e00082-17 (2017)

PubMed: 28694333

Ma, Zhiyu et al. Neuromedin B regulates steroidogenesis, cell viability and apoptosis in rabbit Leydig cells Gen Comp Endocrinol, 288, 113371 (2020)

PubMed: 31857076

Zhang, Jinlong et al. Activation of Autophagy by Low-Dose Silica Nanoparticles Enhances Testosterone Secretion in Leydig Cells Int J Mol Sci, 23, 3104 (2022)

PubMed: 35328525

Hu, Jiahui et al. ERO1α inhibits cell apoptosis and regulates steroidogenesis in mouse granulosa cells Mol. Cell. Endocrinol., 511, 110842 (2020)

PubMed: 32376276