CYP51/PD-L1-IN-3

SKU: orb2277720

Description

CYP51/PD-L1-IN-3 (compound L21), a quinazoline with antifungal properties, serves as a dual inhibitor targeting CYP51 (IC50: 0.205 μM) and PD-L1 (IC50: 0.039 μM). This compound promotes early fungal apoptosis, diminishes intracellular concentrations of IL-2, NLRP3, and NF-κBp65 proteins, incites mitochondrial impairment and ROS accumulation, and culminates in fungal cell lysis and death [1].

Research Area

,Others

Key Properties

• MW: 468.55
• Purity: 98.00%
• Formula: C₂₇H₂₈N₆O₂

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only