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DLin-MC3-DMA

SKU: orb507413

Description

D-Lin-MC3-DMA(MC3) is the most potent cationic lipid that has been synthesized for Lipid nanoparticles (LNPs) to deliver the siRNA.

Research Area

Product Categories/Products/Small Molecules

Images & Validation

Application Notes
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.

Key Properties

CAS Number1224606-06-7
MW641.61
Purity> 98%
FormulaC43H79NO2
SMILESCCCCC/C=C\C/C=C\CCCCCCCCC(OC(=O)CCCN(C)C)CCCCCCCC/C=C\C/C=C\CCCCC

Storage & Handling

StoragePure form: -20°C/3 years,4°C/2 years; In solvent: -20°C/1 month
Expiration Date12 months from date of receipt.
Hazard InformationNon-Toxic
DisclaimerFor research use only

Alternative Names

1224606-06-7, D-Lin-MC3-DMA, (6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

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Ye Zeng 1, Mariona Estapé Senti 2, M Clara I Labonia 3, Panagiota Papadopoulou 1, Maike A D Brans 3, Inge Dokter 3 4, Marcel H Fens 5, Alain van Mil 3 4, Joost P G Sluijter 3 4, Raymond M Schiffelers 2, Pieter Vader 2 3, Alexander Kros 1 Fusogenic Coiled-Coil Peptides Enhance Lipid Nanoparticle-Mediated mRNA Delivery upon Intramyocardial Administration ACS Nano, 17(23), 23466–23477 (2023)

Applications

Cell Screening

Reactivity

Human

Available Sizes

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25 mg
$ 240.00
100 mg
$ 650.00
250 mg
$ 980.00
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