ECE2 Antibody (Center)

SKU: orb134903

Description

Rabbit polyclonal to ECE2. Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Cardiovascular Disease,Neuroscience,Crown Antibodies;Primary Antibodies;Cardiovascular;Neuroscience;Signal Transduction

Images & Validation

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Item 1 of 2

Tested Applications	IHC-P, WB
Dilution Range	IHC-P: 1:25, WB: 1:1000
Reactivity	Human
Predicted Reactivity	Mouse

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Isotype	Rabbit IgG
Clone No.	RB43866
Immunogen	Synthetic Peptide
Target	This ECE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-579 amino acids from the Central region of human ECE2.
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Form/Appearance	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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anti ECE2 antibody, anti KIAA0604 antibody, anti Endothelin-converting enzyme 2 antibody, anti Methyltransferase-like region antibody, anti Endothelin-converting enzyme 2 region antibody

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Quick Database Links

Gene Symbol

This ECE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-579 amino acids from the Central region of human ECE2.

UniProt

O60344

RefSeq (Protein):NP_055508.3, NP_001032401.1, NP_001093591.1, NP_115707.2, NP_001093590.1

UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

Protein	NP_055508.3, NP_001032401.1, NP_001093591.1, NP_115707.2, NP_001093590.1

Protocol Information

Western Blot (IB, immunoblot)

View Protocol

IHC-P

Immunohistochemistry Paraffin