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EGFR kinase inhibitor 7

SKU: orb2663652

Description

EGFRkinase inhibitor 7 (compound 18i) is an EGFR inhibitor with an IC50 of 42.3 nM, exhibiting anticancer properties. This compound demonstrates significant in vitro cytotoxicity and capacity to induce apoptosis. Furthermore, EGFRkinase inhibitor 7 displays anti-proliferative activity against human colon cancer cell line HCT116 and human non-small cell lung cancer cell line A549, with IC50 values of 4.82 µM and 1.43 µM, respectively.

Research Area

,Tyrosine Kinase/Adaptors|||Angiogenesis|||Apoptosis|||JAK/STAT signaling

Images & Validation

Key Properties

MW653.45
Purity98.00%
FormulaC28H26Cl2FN3O3SSe

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information