EGFR/CDK2-IN-2

SKU: orb2277731

Description

EGFR/CDK2-IN-2 (compound 6a) is a dual inhibitor targeting EGFR and CDK-2, with IC50 values of 19.6 nM and 87.9 nM, respectively. It induces apoptosis in MCF-7 cells and arrests cell cycle progression in the S phase, demonstrating notable anticancer activity with an IC50 of 0.39 μM [1].

Research Area

,JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis

Key Properties

• MW: 884.99
• Purity: 98.00%
• Formula: C₄₉H₃₂N₁₂O₂S₂

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only