EGFR/CDK2-IN-3

SKU: orb2277730

Description

EGFR/CDK2-IN-3 (compound 4b) is a dual inhibitor of EGFR and CDK-2 with IC50 values of 71.7 nM and 113.7 nM, respectively. It induces apoptosis in MCF-7 cells, arrests the cell cycle in the S phase, and exhibits significant anti-cancer cell toxicity, inhibiting MCF-7 cells with an IC50 of 3.16 μM [1].

Research Area

,Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

Key Properties

• MW: 512.58
• Purity: 98.00%
• Formula: C₃₀H₂₀N₆OS

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only