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EPZ005687

SKU: orb180981

Description

EPZ-005687 is a potent and selective inhibitor of EZH2 with Ki of 24 nM, 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Images & Validation

Key Properties

CAS Number[1396772-26-1]
MW539.6679
FormulaC32H37N5O3
SMILESO1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])([H])C1C([H])=C([H])C(=C([H])C=1[H])C1=C([H])C(C(N([H])C([H])([H])C2C(N([H])C(C([H])([H])[H])=C([H])C=2C([H])([H])[H])=O)=O)=C2C([H])=NN(C2=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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EPZ005687

Chemical structure of EPZ005687.

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EPZ005687 (orb180981)

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Available Sizes

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1 ml x 10 mm (in DMSO)
$ 390.00
100 mg
$ 950.00
250 mg
$ 1,670.00
1 g
$ 2,850.00
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