ESR1 isoform1 Antibody(C-term)

SKU: orb107108

Description

Rabbot polyclonal to ESR1 isoform1. This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Product Categories/Products/Antibodies/Primary Antibodies,Epigenetics,Primary Antibodies;Cancer;Neuroscience;Signal Transduction;SARS-Human interaction partners

Images & Validation

• Tested Applications: IF, WB
• Dilution Range: WB: 1:1000, IF/ICC: 1:10-50
• Reactivity: Human
• Predicted Reactivity: Equine, Mouse, Porcine, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Clone No.: RB41149
• Immunogen: Synthetic Peptide
• Target: ESR1
• Molecular Weight: 66216
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti ESR1 antibody, anti ESR antibody, anti NR3A1 antibody, anti Estrogen receptor antibody, anti ER-alpha antibody, anti Estradiol receptor antibody, anti Nuclear receptor subfamily 3 group A member 1 antibody

Quick Database Links

Gene Symbol

ESR1

UniProt

P03372

RefSeq (Protein):NP_001116214.1, NP_001116213.1, NP_001116212.1, NP_000116.2