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FLT3 (C) Antibody, Rabbit Polyclonal

SKU: orb66757

Description

Rabbit polyclonal to FLT3.FMS-related tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase that regulates hematopoiesis.Upon ligand binding, the receptor is activated inducing a homodimer formation in the plasmamembrane leading to autophosphorylation of the receptor. Activated FLT3 can also phosphorylateand activate multiple cytoplasmic effector molecules in pathways implicated in apoptosis, proliferationand differentiation of hematopoietic cells in bone marrow. Mutations that result in constitutiveactivation of this receptor are associated with acute myeloid leukemia and acute lymphoblasticleukemia.

Research Area

Product Categories/Products/Antibodies,Epigenetics,Product Categories/Research Area,Cancer,Cardiovascular Disease

Images & Validation

Tested ApplicationsWB
Dilution RangeWB:1:1000-1:5000
ReactivityHuman, Mouse

Key Properties

HostRabbit
ClonalityPolyclonal
ImmunogenC-terminal region of mouse FLT3
Molecular Weight113
PurityAffinity purification
ConjugationUnconjugated

Storage & Handling

Storage-20°C
Buffer/Preservatives0.01% NaN3
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

anti-FLT3 antibody,anti-B230315G04 antibody,anti-CD135 antibody,anti-Flk2 antibody,anti-Flk2 antibody,anti-Flt3 antibody,anti-Ly72 antibody,anti-MGC124377 antibody,anti-MGC124378 antibody,anti-wmfl antibody

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UniProt Details

No UniProt data available

Protocol Information

WB
Western Blot (IB, immunoblot)
View Protocol

Available Sizes

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100 μl
$ 440.00
Choose Conjugation or Carrier Free Version
Free Secondary Antibody (20 ul)0/0

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DispatchUsually dispatched within 5-10 working days.
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