Fludarabine triphosphate trisodium

SKU: orb1983218

Description

Fludarabine triphosphate (F-ara-ATP) trisodium, the principal metabolite of Fludarabine, is a potent, noncompetitive, and specific inhibitor of DNA primase with an IC50 value of 2.3 μM and a Ki of 6.1 μM. It obstructs DNA synthesis by hindering DNA primase and primer RNA formation, while also inhibiting ribonucleotide reductase and DNA polymerase activities, effectively inducing cellular apoptosis [1] [2].

Research Area

,Others

Key Properties

• MW: 591.12
• Purity: 98.00%
• Formula: C₁₀H₁₂FN₅Na₃O₁₃P₃

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only