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Fosmidomycin

SKU: orb2564498

Description

Fosmidomycin is an orally administered antibiotic that demonstrates antimalarial properties by inhibiting 1-deoxy-D-xylulose 5-phosphate (DOXP) reductoisomerase. It effectively inhibits the P. falciparum strains 3D7, HB3, Dd2, and A2, with IC 50 values of 150, 71, 170, and 150 ng/mL, respectively. Fosmidomycin works synergistically with Clindamycin and alleviates malaria in a mouse model.

Images & Validation

Key Properties

CAS Number66508-53-0
MW183.10
Purity98.00%
FormulaC4H10NO5P
SMILESO=CN(O)CCCP(=O)(O)O

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information