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Description
Research Area
,Recombinant-Protein
Images & Validation
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| Application Notes |
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Key Properties
−| Expression System | HEK293 Cells |
|---|---|
| Biological Origin | Human |
| Biological Activity | LGALS9 (Galectin 9) is a Protein Coding gene. 6 alternatively spliced human isoforms have been reported. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. LGALS9 is broadly expressed in the spleen, stomach, and other tissues. Diseases associated with LGALS9 include Dengue Virus and Adhesive Otitis Media. An important paralog of this gene is LGALS9B.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Tag | N-hFc |
| Expression Region | A DNA sequence encoding the human LGALS9 (NP_002299.2) (Ala2-Thr323) was expressed with the Fc region of human IgG1 at the N-terminus. Predicted N terminal: Glu |
| MW | 61.8 kDa (predicted); 64.8 kDa (reducing conditions) |
| Purity | 94.60% |
Storage & Handling
−| Storage | -20°C |
|---|---|
| Expiration Date | 6 months from date of receipt. |
| Disclaimer | For research use only |
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Human Galectin 9 Protein, hFc Tag [orb757445]
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
The protein has a predicted molecular mass of 61.9 kDa after removal of the signal peptide.The apparent molecular mass of hFc-Galectin 9 is approximately 70-100 kDa due to glycosylation.
Mammalian
10 μg, 100 μg, 50 μg
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