GAP43 (Phospho-Ser41) Antibody

SKU: orb14962

Description

GAP43 encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

Research Area

Product Categories/Products/Antibodies

Images & Validation

• Tested Applications: IF
• Dilution Range: Immunofluorescence: 1:100 - 1:200
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Target: The antibody detects endogenous level of GAP43 only when phosphorylated at Ser41
• Protein Sequence: Peptide sequence around phosphorylation site of Ser41 (Q-A-S(p)-F-R) derived from Human GAP43
• Molecular Weight: Predicted MW: 43kd
• Purity: Purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Store at -20°C for long term preservation (recommended). Store at 4°C for short term use
• Form/Appearance: Supplied at 1.0mg/mL in phosphate-buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

The antibody detects endogenous level of GAP43 only when phosphorylated at Ser41

UniProt

P17677