GAP43 Rabbit mAb

SKU: orb1951585

Description

This protein is associated with nerve growth. It is a major component of the motile growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.,,,,,1,,1,1,1,0,1,1701055481,0,0,0,0,0,0,0,1701055481,0,-1,-1,0,0 323585,57,58918,JAM1 Rabbit mAb,0,10,JAM1-Rabbit-mAb,JAM1 Rabbit mAb,,0,50ul,249,249,0,0,0,58,ABWAY,CY5635,CY5635,0,0,0,Yes,Rabbit Monoclonal Antibody,"Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Images & Validation

• Tested Applications: FC, ICC, IHC, IP, WB
• Dilution Range: WB 1:10000~1:50000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 FC 1:20
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human GAP43
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GAP43, Axonal membrane protein GAP-43, B-50, Growth associated protein 43, Neural phosphoprotein B-50, Neuromodulin, PP46, GAP-43, Protein F1;

All lanes use the Antibody at 1:2W dilution for 1 hour at room temperature.

Immunohistochemical analysis of paraffin-embedded human stomach, using GAP43 Antibody.

Western blot analysis of GAP43 expression in SH-SY5Y cell lysate.