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GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated

SKU: orb1961885

Description

Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. It also can bridge virus envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry by apoptotic mimicry.

Research Area

,Recombinant-Protein

Images & Validation

Key Properties

Expression SystemHEK293 Cells
Biological OriginHuman
Biological ActivityHuman Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. It also can bridge virus envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry by apoptotic mimicry.
TagC-Avi-6xHis
Expression RegionAla31-Ala678
MW80-90 KDa (reducing condition)
Purity98.00%
Protein SequenceAla31-Ala678

Storage & Handling

Storage-20°C
Expiration Date6 months from date of receipt.
DisclaimerFor research use only
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UniProt Details

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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20 μg
$ 460.00
100 μg
$ 1,070.00
DispatchUsually dispatched within 5-10 working days
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