GPX4-IN-7

SKU: orb2277694

Description

GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment. Exhibiting potent antitumor properties, it inhibits HCT-116 cell growth with an IC50 of 0.49 μM. This compound also facilitates GPX4 degradation, leading to lipid ROS accumulation, thereby inducing ferroptosis [1].

Research Area

,Apoptosis

Key Properties

• MW: 478.93
• Purity: 98.00%
• Formula: C₂₅H₂₃ClN₄O₄

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only