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Description
Research Area
,Recombinant-Protein
Images & Validation
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Key Properties
−| Expression System | HEK293 Cells |
|---|---|
| Biological Origin | Mouse |
| Biological Activity | Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. |
| Tag | C-6xHis |
| Expression Region | Gly19-Ser247 |
| MW | 35 KDa (reducing condition) |
| Purity | 98.00% |
| Protein Sequence | Gly19-Ser247 |
Storage & Handling
−| Storage | -20°C |
|---|---|
| Expiration Date | 6 months from date of receipt. |
| Disclaimer | For research use only |
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Quick Database Links
UniProt
UniProt Details
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Protocol Information
Protein Handling and Storage Guide
Protein Handling Guide
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