HCH6-1

SKU: orb692097

Description

HCH6-1 is a competitive antagonist of Formyl peptide receptor 1 (FPR1), an emerging therapeutic target for the discovery of drugs to treat neutrophilic inflammatory diseases. HCH6-1 is a selective FPR1 inhibitor and has protective effects against acute lung injury (ALI). HCH6-1 inhibits superoxide anion generation, elastase release, and chemotaxis in human neutrophils activated by fMLF (an FPR1 agonist).

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Key Properties

• CAS Number: [1435265-06-7]
• MW: 469.53
• Formula: C₂₈H₂₇N₃O₄
• SMILES: O=C([C@]([H])(C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)N([H])C(C1C([H])=C([H])C([H])=C([H])C=1[H])=O)N([H])[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H]

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only