HNRNPD Antibody (N-term)

SKU: orb107064

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Description

Rabbot polyclonal to HNRNPD. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Product Categories/Products/Antibodies/Primary Antibodies,Epigenetics,Crown Antibodies;Primary Antibodies;Ribonucleoprotein;Viral nucleoprotein

Images & Validation

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Tested Applications	IF, WB
Dilution Range	WB: 1:1000, IF/ICC: 1:10-50
Reactivity	Human
Predicted Reactivity	Mouse, Rat

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Isotype	Rabbit IgG
Clone No.	RB30287
Immunogen	Synthetic Peptide
Target	HNRNPD
Molecular Weight	38434
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Form/Appearance	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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anti HNRNPD antibody, anti AUF1 antibody, anti HNRPD antibody, anti Heterogeneous nuclear ribonucleoprotein D0 antibody, anti AU-rich element RNA-binding protein 1 antibody

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Quick Database Links

Gene Symbol

HNRNPD

UniProt

Q14103

RefSeq (Protein):NP_112737.1, NP_112738.1, NP_002129.2, NP_001003810.1

UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

Protein	NP_112737.1, NP_112738.1, NP_002129.2, NP_001003810.1

Protocol Information

Western Blot (IB, immunoblot)

View Protocol

Immunofluorescence