HPV16 E6 Rabbit Polyclonal Antibody

SKU: orb10837

Description

HPV16 E6 Rabbit Polyclonal Antibody

Research Area

HPV, Infectious Disease, Human Papillomavirus, Infectious Disease

Images & Validation

• Tested Applications: FC, IF, IHC-Fr, IHC-P
• Dilution Range: IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1ug/Test
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human HPV16 E6 (85-158/158aa)
• Target: L2
• Molecular Weight: 11 kDa
• Purification: affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

E6; Human Papilloma Virus; Human papillomavirus type 16 E6; Human papillomavirus type 16; Protein E6; E6 protein; HPV16 E6; HPV16-E6; VE6_HPV16.

Quick Database Links

Gene Symbol

L2

Yu, Lan et al. Disruption of human papillomavirus 16 E6 gene by clustered regularly interspaced short palindromic repeat/Cas system in human cervical cancer cells Onco Targets Ther, 8, 37-44 (2015)

PubMed: 25565864

Applications

WB

Reactivity

Human

Hu, Zheng et al. TALEN-mediated targeting of HPV oncogenes ameliorates HPV-related cervical malignancy J Clin Invest, 125, 425-436 (2015)

PubMed: 25500889

Applications

WB

Wang, Qiqi et al. HPV16 E6 promotes cervical cancer cell migration and invasion by downregulation of NHERF1 Int. J. Cancer, (2018)

PubMed: 30230542

Li, Mengtao et al. Exposure to microbial metabolite butyrate prolongs the survival time and changes the growth pattern of HPV16 E6/E7-immortalized keratinocytes in vivo Am J Pathol, (2021)

PubMed: 34214507