HSP90-IN-33

SKU: orb2695276

Description

HSP90-IN-33 (compound 24e) is an effective Hsp90 inhibitor, demonstrating dissociation constants (Kd) of ≥200 µM for Hsp90α and 7.3 µM for Hsp90β. This compound induces cellular apoptosis (apoptosis) and arrests the cell cycle at the G0/G1 phase. Additionally, HSP90-IN-33 reduces the protein expression of ERα, CDK4, and Akt.

Research Area

,Apoptosis|||Metabolism|||Cytoskeletal Signaling

Key Properties

• MW: 450.36
• Formula: C₂₁H₂₅Cl₂N₅O₂

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only