Human 4-1BB Ligand protein

SKU: orb107685

Description

Recombinant Human 4-1BBL is a member of the tumor necrosis factor (TNF) receptor family. This receptor contributes to the clonal expansion,survival, and development of T cells. In addition, 4-1BBL expression is found on dendritic cells, follicular dendritic cells, naturalkiller cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has been shown to interact with TRAF2.The human 4-1BBL gene codes for a 254 amino acid type II transmembrane containing a 28 amino acid cytoplasmic domain, a21 amino acid transmembrane domain, and a 205 amino acid extracellular domain (ECD). The human 41BBLECD shares 32 %and 35 % a.a. identity with murine and rat ECD.

Images & Validation

• Tested Applications: HPLC, SDS-PAGE

Key Properties

• Biological Origin: E.coli
• Target: 4-1BB Ligand
• Conjugation: Unconjugated
• MW: 19.4 kDa
• Purity: > 95 % by SDS-PAGE and HPLC analyses.
• Protein Sequence: REGPELSPDD PAGLLDLRQG MFAQLVAQNV LLIDGPLSWY SDPGLAGVSLTGGLSYKEDT KELVVAKAGV YYVFFQLELR RVVAGEGSGS VSLALHLQPLRSAAGAAALA LTVDLPPASS EARNSAFGFQ GRLLHLSAGQ RLGVHLHTEARARHAWQLTQ GATVLGLFRV TPEIPAGLPS PRSE

Storage & Handling

• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Human 4-1BB Ligand protein

SDS-PAGE analysis of Human 4-1BB Ligand protein

Quick Database Links

Gene Symbol

4-1BB Ligand