Human anti-SARS-CoV & CoV-2 Spike antibody (IgM), clone CR3022

SKU: orb1178881

Description

Human anti-SARS-CoV-2 Spike Antibody [CR3022] recognizes human SARS-CoV and CoV-2 Spike protein with high affinity. The binding site is amino acids 318-510 (RBD, Receptor Binding Domain) in the S1 subunit of the Spike protein. Coronavirus Spike protein conducts the process that interacts with cellular receptor and membrane fusion to allow virus entering into target cells. Spike protein also can be used to define the specificity of the virus and be used as a critical target for vaccine design. The glycosylated Spike protein can be detected in the virus-infected cell and cell culture medium. The RBD is responsible for recognizing the cell surface receptor.

Research Area

Product Categories/Antibodies/Primary Antibodies,Product Categories/Antibodies

Images & Validation

• Tested Applications: ELISA
• Dilution Range: ELISA 1:5000-20000
• Reactivity: Virus

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgM
• Clone No.: CR3022
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: Phosphate Buffered Saline, pH 7.4.
• Concentration: 0.5 mg/mL
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only