Human IFN-alpha / beta R2 Protein, Fc Tag

SKU: orb257561

Description

Human IFNAR2, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Ile 27 - Lys 243 (Accession # P48551-2).

Research Area

Disease Biomarkers

Images & Validation

• Application Notes:
  This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.4 kDa. The protein migrates as 66-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

• Expression System: HEK293
• Biological Origin: Human
• Biological Activity: Loaded Human IFN-alpha 1, His Tag on HIS1K Biosensor, can bind Human IFNAR2, Fc Tag with an affinity constant of 19.5 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).
• Target: IFN-alpha/beta R2
• Reactivity: Human
• Tag: C-Fc
• Expression Region: Ile 27 - Lys 243
• Endotoxins: 1.0 EU per μg
• Conjugation: Unconjugated
• MW: 51.4 kDa
• Purity: 95%
• Protein Sequence: NP_997467.1

Storage & Handling

• Storage: -20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
• Form/Appearance: Powder
• Buffer/Preservatives: Tris with Glycine, Arginine and NaCl, pH 7.5
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

SDS-PAGE analysis of Human IFN-alpha/beta R2 protein

Loaded Human IFN-alpha 1, His Tag (Cat. No. orb735041) on HIS1K Biosensor, can bind Human IFNAR2, Fc Tag (Cat. No. orb257561) with an affinity constant of 19.5 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Quick Database Links

Gene Symbol

IFN-alpha/beta R2

UniProt

P48551

RefSeq (Protein):NP_997467.1