Human IFN-omega protein

SKU: orb107738

Description

Interferon-Omega (IFN-Omega) coded by IFNW1 gene in human, is a number of the type I interferon family, which includes IFN-a,IFN-beta, and IFN-Omega. The IFNAR-1/IFNAR-2 receptor complex can help with the signal transduction, followed the antiviral or theantiproliferative actions. IFN-Omega is derived from IFN-a/beta and share 75% sequence with IFN-a. It has two intramolecular disulfidebonds which are crucial for activities. Mire-Sluis et al have described bioassays for IFN-a, IFN-beta, and IFN-Omega that exploit theability of these factors to inhibit proliferation of TF-1 cells induced by GM-CSF. The bioassays can be used also with Epo andTF-1 cells, or Epo and Epo-transfected UT-7 cells.

Images & Validation

• Tested Applications: HPLC, SDS-PAGE

Key Properties

• Biological Origin: E.coli
• Target: IFN-omega
• Conjugation: Unconjugated
• MW: 19.9 kDa
• Purity: > 97% by SDS-PAGE and HPLC analyses
• Protein Sequence: CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL KDRRDFRFPQ EMVKGSQLQKAHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCLLQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMKSLFLSTNMQE RLRSKDRDLG SS

Storage & Handling

• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Human Interferon-Omega protein

SDS-PAGE analysis of Human IFN-omega protein

Quick Database Links

Gene Symbol

IFN-omega