Human IL-16(130a.a.) protein

SKU: orb107756

Description

Human Interleukin-16 (IL-16) is also called lymphocyte chemoattractant factor (LCF) and it has three isoforms which arecleaved from pre-Interleukin-16. IL-16 is mostly secreted by lymphocytes, epithelial cells, eosinophils, and CD8+ T cells. It hasmany functions including induction of the IL-2RF on T cells, suppression of human immunodeficiency virus (HIV) replication,inhibition of T-cell antigen receptor/CD3 mediated T-cell stimulation in mixed lymphocyte reactions and so on. It signals throughCD4 receptor. Furthermore, recombinant human IL-16(130 a.a.) contains 130 amino acid residues and it shares 85 % a.a.sequence identity with murine IL-16.

Images & Validation

• Tested Applications: HPLC, SDS-PAGE

Key Properties

• Biological Origin: E.coli
• Target: IL-16
• Conjugation: Unconjugated
• MW: 13.4 kDa
• Purity: > 95 % by SDS-PAGE and HPLC analyses.
• Protein Sequence: MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLTINRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQSKETTAAGDS

Storage & Handling

• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 m filtered concentrated solution in 20 mM Tris, 150 mM NaCl, pH 7.0.
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Human Interleukin-16 protein

Quick Database Links

Gene Symbol

IL-16