Human Maspin protein

SKU: orb107777

Description

Mammary serine protease inhibitor (Maspin) is a non-inhibitory serpin that is expressed predominantly in normal mammaryepithelial cells but at significantly reduced levels or absent in most breast carcinomas. It has the ability to block the growth,invasiveness, and metastatic potential of breast and lung tumors. This anti-tumor activity is achieved, in part, by the ability ofMaspin to inhibit angiogenesis and to preferentially promote apoptosis of tumor cells.

Images & Validation

• Tested Applications: HPLC, SDS-PAGE

Key Properties

• Biological Origin: E.coli
• Target: Maspin
• Conjugation: Unconjugated
• MW: 42.2kDa
• Purity: > 95% by SDS-PAGE and HPLC analyses
• Protein Sequence: MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHFENVKDIPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVDFKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESETKECPFRLNKT DTKPVQMMNM EATFCMGNID SINCKIIELP FQNKHLSMFI LLPKDVEDESTGLEKIEKQL NSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSEDTSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRHNKTRNIIFFG KFCSP

Storage & Handling

• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Human Mammary Serine Protease Inhibitor protein

Quick Database Links

Gene Symbol

Maspin