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Human OSMR Protein, His Tag

SKU: orb1496186
ActiveBiologically Active

Description

Oncostatin-M-specific receptor subunit beta (OSMRB) alos know as Interleukin-31 receptor subunit beta (IL-31RB), is an alternative subunit (OSMRβ) for an OSM receptor complex (a heterodimer of gp130 and OSMRβ), that is activated by OSM but not by LIF. OSMR beta associates with the low affinity OSM·gp130 complex to form a high affinity heterodimeric receptor that is capable of transducing OSM-specific signaling events.

Research Area

Immunology & Inflammation

Images & Validation

Application Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 83.0 kDa. The protein migrates as 105-125 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

Expression SystemHEK293
Biological OriginHuman
TargetOSMR
ReactivityHuman
TagC-10×His
Expression RegionGlu 28 - Met 740
Endotoxins1.0 EU per μg
ConjugationUnconjugated
MW83.0 kDa
Purity95%
Protein SequenceGlu 28 - Met 740

Storage & Handling

Storage-20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
Form/AppearancePowder
Buffer/PreservativesPBS, pH 7.4
Expiration Date6 months from date of receipt.
DisclaimerFor research use only

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UniProt Details

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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Human OSMR Protein, His Tag (orb1496186)

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100 μg
$ 750.00
1 mg
$ 4,090.00
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