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Description
Images & Validation
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Key Properties
−| Source | Yeast |
|---|---|
| Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by neutralizing the stimulation of U937 cells is less than 10 ng/ml, corresponding to a specific activity of > 1.0 x 105 IU/mg in the presence of 10 ng/mL soluble rHuRANKL (sRANKL). |
| Target | TNFRSF11B |
| Reactivity | Human |
| Conjugation | Unconjugated |
| MW | 17.2 kDa |
| Purity | > 95% by SDS-PAGE and HPLC analyses. |
Storage & Handling
−| Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
|---|---|
| Buffer/Preservatives | Lyophilized: 0.2 μm filtered concentrated solution in 20 mM PB, pH 6.0, 150 mM NaCl, 0.02 % Tween-80 |
| Expiration Date | 6 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−Similar Products
−Recombinant Human Osteoprotegerin/Fc Chimera (rHuOPG-Fc) [orb1495077]
> 90% by SDS-PAGE and HPLC analyses.
Recombinant OPG/Fc contains 412 amino acid residues, including 180 residues from mature OPG (a.a 22-201) and 232 residues from the Fc protein of human IgG1, and has a calculated molecular mass of 46.5 kDa. As a result of glycosylation, the recombinant OPG/Fc migrates as a 49 kDa protein in SDS-PAGE under reducing conditions.
Pichia. Pastoris.
1 mg, 50 μg, 10 μg

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