Human sTRAIL Receptor-2 protein

SKU: orb107809

Description

Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2 (TRAIL-R2) is a cell-surface receptor involved in tumornecrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.1 The death ligand TRAIL bears highpotential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancercells.2 TRAIL-R2 has been shown to be associated with a decrease in the survival rates of breast cancer patients.

Images & Validation

• Tested Applications: HPLC, SDS-PAGE

Key Properties

• Biological Origin: E.coli
• Target: sTRAIL Receptor-2
• Conjugation: Unconjugated
• MW: 14.8 kDa
• Purity: > 97% by SDS-PAGE and HPLC analyses
• Protein Sequence: ESALITQQDL APQQRAAPQQ KRSSPSEGLC PPGHHISEDG RDCISCKYGQ DYSTHWNDLLFCLRCTRCDS GEVELSPCTT TRNTVCQCEE GTFREEDSPE MCRKCRTGCP RGMVKVGDCTPWSDIECVHK ES

Storage & Handling

• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Human Soluble Tumor Necrosis Factor-Related Apoptosis-inducing Ligand Receptor-2 / TNFRSF10B protein

Quick Database Links

Gene Symbol

sTRAIL Receptor-2