Human UBC1 protein

SKU: orb107811

Description

Ubiquitin-conjugating enzyme E2 K is a protein that in humans is encoded by the UBE2K gene. The protein encoded by thisgene belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin.This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in thedegradation of huntingtin and suppression of apoptosis

Images & Validation

• Tested Applications: HPLC, SDS-PAGE

Key Properties

• Biological Origin: E.coli
• Target: UBC1
• Conjugation: Unconjugated
• MW: 23.4 kDa
• Purity: > 95% by SDS-PAGE and HPLC analyses
• Protein Sequence: MHHHHHHAMA NIAVQRIKRE FKEVLKSEET SKNQIKVDLV DENFTELRGEIAGPPDTPYE GGRYQLEIKI PETYPFNPPK VRFITKIWHP NISSVTGAICLDILKDQWAA AMTLRTVLLS LQALLAAAEP DDPQDAVVAN QYKQNPEMFKQTARLWAHVY AGAPVSSPEY TKKIENLCAM GFDRNAVIVA LSSKSWDVETATELLLSN

Storage & Handling

• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Human Ubiquitin Conjugating Enzyme E2 K, His protein

SDS-PAGE analysis of Human UBC1 protein

Quick Database Links

Gene Symbol

UBC1