HXR9 hydrochloride

SKU: orb1981246

Description

HXR9 hydrochloride, a cell-permeable peptide and competitive antagonist of the HOX/PBX interaction, selectively reduces cell proliferation and induces apoptosis in cells with elevated HOXA/PBX3 gene expression, notably MLL-rearranged leukemic cells [1] [2] [3]. By inhibiting the interaction between HOX proteins and the transcription factor PBX, which associates with HOX proteins in paralogue groups 1 to 8, it disrupts a critical regulatory mechanism in these cells.

Key Properties

• MW: 2754.67
• Purity: 98.00%
• Formula: C₁₁₉H₁₉₄ClN₅₃O₂₀S

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only