ICCB-19 hydrochloride

SKU: orb1089588

Description

ICCB-19 hydrochloride is an inhibitor of TNFRSF1A Associated Via Death Domain (TRADD) with IC50 of 1.12 μM and 2.01 μM for protecting Velcade-induced apoptosis in Jurkat cells and protecting RDA in MEFs, respectively. ICCB-19 indirectly inhibits Receptor-interacting serine/threonine-protein kinase 1 (RIPK1). ICCB-19 effectively induces autophagy.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Key Properties

• CAS Number: [1803605-68-6]
• MW: 291.840580463409
• Formula: C₁₂H₂₂CLN₃OS
• SMILES: Cl.C1(NC(=O)CSC2NCCN=2)CCCCCC1

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only