Indibulin

SKU: orb2703267

Description

Indibulin is a synthetic small molecule with antimitotic and potential antineoplastic activities. Indibulin binds to a site on tubulin that is different from taxane- or Vinca alkaloid-binding sites, destabilizing tubulin polymerization and inducing tumor cell cycle arrest and apoptosis. This agent has been shown to be active against multidrug-resistant (MDR) and taxane- resistant tumor cell lines. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

Key Properties

• CAS Number: [204205-90-3]
• MW: 389.83
• Formula: C₂₂H₁₆ClN₃O₂
• SMILES: O=C(NC1=CC=NC=C1)C(C2=CN(CC3=CC=C(Cl)C=C3)C4=C2C=CC=C4)=O

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only