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Integrin alpha V beta 3 Protein, Human, Recombinant (His)
SKU: orb1954183
Description
Research Area
,Recombinant-Protein
Images & Validation
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| Application Notes |
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Key Properties
−| Expression System | HEK293 Cells |
|---|---|
| Biological Origin | Human |
| Biological Activity | Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. |
| Tag | C-His |
| Expression Region | A DNA sequence encoding the extracellular domain (Met1-Val992) of human ITGAV (P06756) was fused with a his tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the extracellular domain (Met1-Asp718) of human ITGB3 (P05106) constructed the plasmid 2. The two plasmids were co-expressed and the human ITGAV&ITGB3 heterodimer was purified. Predicted N terminal: Phe31 & Gly27 |
| MW | 193.32 kDa (predicted) |
| Purity | SDS-PAGE: 94.9%; SEC-HPLC: 91.6% |
Storage & Handling
−| Storage | -20°C |
|---|---|
| Expiration Date | 6 months from date of receipt. |
| Disclaimer | For research use only |
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Protein Handling and Storage Guide
Protein Handling Guide
Integrin alpha V beta 3 Protein, Human, Recombinant (His) (orb1954183)
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