Integrin alpha V + beta 6 Antibody

SKU: orb2315366

Description

Integrin alpha V + beta 6 Antibody

Research Area

,Immunology|Lung Cancer|Signal Transduction

Images & Validation

• Tested Applications: ELISA, FC, IF, WB
• Dilution Range: ELISA (For coating use Ab at 1-5ug/ml, order Ab without BSA); Immunoprecipitation (1-2ug/500ug protein); ,Flow Cytometry (0.5-1ug/million cells); Immunofluorescence (1-2ug/ml); Western Blot (0.5-1ug/ml);,Optimal dilution for a specific application should be determined.
• Reactivity: Human
• Application Notes:
  Positive Control: Squamous cell carcinoma cells. A375M melanoma cell line. A549 cell line

Key Properties

• Host: Rat
• Clonality: Monoclonal
• Isotype: IgG2a
• Clone No.: AvB6 53a.2
• Immunogen: Mouse fibroblasts retrovirally infected with cDNA to human beta6; Cells expressed a mouse/human avb6 chimera.
• Target: ITGAV
• Source/Expression System: Bioreactor
• Molecular Weight: 150-160kDa under non-reducing conditions. Under reducing conditions|cleaved into 2 bands of ~125-130kDa +20-25kDa
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Concentration: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

antigen identified by monoclonal antibody L230; CD 51; CD51; Integrin alpha five; integrin alpha V beta 3; Integrin alpha-V light chain; integrin alphaVbeta3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); ITGAV; MSK 8; Msk8; Vitronectin receptor subunit alpha; VNRA; VTNR; ITGB6, Integrin, beta 6

Quick Database Links

Gene Symbol

ITGAV

UniProt

P06756, P18564

NCBI Gene ID

3685, 3694