Interleukin-1β Convertase Substrate

SKU: orb2693984

Description

IL-1β converting enzyme (ICE, now called caspase-1), a cytosolic enzyme, is responsible for the cleavage of the inactive precursor protein to the active IL-1β. Similarly, caspase-1 hydrolyzes this 14-amino acid peptide that corresponds to the native cleavage site sequence around Asp11?-Ala11?. The peptide is also able to inhibit the cleavage of the precursor to the mature protein.

Key Properties

• Target: others
• CAS Number: 143305-11-7
• MW: 1584.71
• Purity: ≥95%
• Formula: C₆₈H₁₀₅N₂₁O₂₃
• Protein Sequence: NEAYVHDAPVRSLN

Storage & Handling

• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

others