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Description
Research Area
,Recombinant-Protein
Images & Validation
−
Key Properties
−| Expression System | E. coli |
|---|---|
| Biological Origin | Human |
| Biological Activity | Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis. |
| Tag | C-6xHis |
| Expression Region | Met1-Gln498 |
| MW | 62 KDa (reducing condition) |
| Purity | 98.00% |
| Protein Sequence | Met1-Gln498 |
Storage & Handling
−| Storage | -20°C |
|---|---|
| Expiration Date | 6 months from date of receipt. |
| Disclaimer | For research use only |
Similar Products
−Recombinant Human IRF5 Protein, His Tag [orb1552160]
≥90% as determined by SDS-PAGE
This protein contains the human IRF5(Met1-Gln498) was fused with the C-terminal His Tag and expressed in E. coli.
100 μg, 50 μgIKBKB Protein, Human, Recombinant (E. coli, His) [orb1978383]
98.00%
92.5 kDa (predicted)
1 mg, 100 μg, 20 μg
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Protocol Information
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Protein Handling Guide
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