ITGA4 (C) Antibody, Rabbit Polyclonal

SKU: orb67043

Description

Rabbit polyclonal to ITGA4.Integrin alpha-4 (ITGA4) is a single-pass type I membrane protein that belongs to the intergrin alphachain family. Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. Theyrecognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin.They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S inVCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T inMADCAM1. On activated endothelial cells, integrin VLA-4 triggers homotypic aggregation for mostVLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with targetcells.

Research Area

Product Categories/Products/Antibodies,Epigenetics,Product Categories/Products/Antibodies/Primary Antibodies

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:500-1:1000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human ITGA4
• Molecular Weight: 115
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-ITGA4 antibody,anti-Integrin alpha4 antibody,anti-CD49 antigenlike family member D antibody,anti-Integrin alphaIV antibody,anti-VLA4 subunit alpha antibody,anti-CD49d antibody,anti- CD49D antibody

Quick Database Links

UniProt

P13612