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IWR-1

SKU: orb180916

Description

IWR-1 (endo-IWR 1) is a Wnt pathway inhibitor with IC50 of 180 nM, induces Axin2 protein levels and promotes β-catenin phosphorylation by stabilizing Axin-scaffolded destruction complexes.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Images & Validation

Key Properties

CAS Number[1127442-82-3]
MW409.4367
FormulaC25H19N3O3
SMILESO=C1C2([H])C3([H])C([H])=C([H])C([H])(C3([H])[H])C2([H])C(N1C1C([H])=C([H])C(C(N([H])C2=C([H])C([H])=C([H])C3C([H])=C([H])C([H])=NC2=3)=O)=C([H])C=1[H])=O

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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IWR-1

Chemical structure of IWR-1

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Protocol Information

IWR-1 (orb180916)

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1 ml x 10 mm (in DMSO)
$ 300.00
100 mg
$ 490.00
250 mg
$ 890.00
1 g
$ 1,670.00
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