JNJ-63576253 (TRC-253)

SKU: orb1089649

Description

JNJ-63576253 (TRC-253) is a potent and selective androgen receptor (AR) Antagonist with IC50 of 6.9 nM. JNJ-63576253 displays robust inhibition in WT and LBD-mutated, enzalutamide-resistant models of prostate cancer.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

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Key Properties

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CAS Number	[2110426-27-0]
MW	502.516
Formula	C₂₃H₂₁F₃N₆O₂S
SMILES	C(F)(F)(C1=CC(N2C(N(C3C=CC(=NC=3)OC3CCNCC3)C3(CCC3)C2=O)=S)=CN=C1C#N)F

Storage & Handling

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Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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