(+)-JNJ-A07

SKU: orb1818753

Description

(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. (+)-JNJ-A07 exerts nanomolar to picomolar activity against a panel of 21 clinical isolates. (+)-JNJ-A07 has a favourable pharmacokinetic profile that results in outstanding efficacy against dengue virus infection in mouse infection models.

Key Properties

• CAS Number: [2135640-93-4]
• MW: 578.96
• Formula: C₂₈H₂₆CLF₃N₂O₆
• SMILES: N1(CCC2=C1C=C(C=C2)OC(F)(F)F)C(C(C1=CC=C(C=C1)Cl)NC1=CC(OCCCC(O)=O)=CC(=C1)OC)=O

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only