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Description
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| Tested Applications | ELISA, FC, WB |
|---|---|
| Dilution Range | WB=1:500-2000, Flow-Cyt=1:100-500, ELISA=1:5000-10000 |
| Reactivity | Human |
| Predicted Reactivity | Mouse |
Key Properties
−| Antibody Type | Primary Antibody |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated synthetic peptide derived from human Josephin-2 (91-188/188aa) |
| Target | JOSD2 |
| Molecular Weight | 21 kDa |
| Purification | affinity purified by Protein A |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Form/Appearance | Liquid |
| Buffer/Preservatives | 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Expiration Date | 12 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−FLJ29018; JOS2_HUMAN; JOSD 2; JOSD2; Josephin 2; Josephin domain containing 2; Josephin domain containing protein 2; Josephin domain-containing protein 2; Josephin-2; Josephin2; SBBI54.
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Quick Database Links
Gene Symbol
JOSD2
UniProt
UniProt Details
− No UniProt data available
Protocol Information
WB
Western Blot (IB, immunoblot)
FC
Flow Cytometry
ELISA
Enzyme-linked Immunosorbent Assay (EIA)
Filter by Applications
Filter by Species
Tao Yuan # 1, Chenming Zeng # 2, Jiawei Liu # 3, Chenxi Zhao 1, Fujing Ge 1, Yuekang Li 1, Meijia Qian 1, Jiamin Du 1, Weihua Wang 1, Yonghao Li 1, Yue Liu 1, Xiaoyang Dai 4, Jianya Zhou 5, Xueqin Chen 6, Shenglin Ma 6, Hong Zhu 7 8, Qiaojun He 9 10, Bo Yang Josephin domain containing 2 (JOSD2) promotes lung cancer by inhibiting LKB1 (Liver kinase B1) activity Signal Transduct Target Ther, 9, 11 (2024)
Applications
WB
Reactivity
Human
Xin Liu a b c † , Yi Fang c † , Mincong Huang d , Shiliang Tu b , Boan Zheng b , Hang Yuan b , Peng Yu b , Mengyao Lan d , Wu Luo c , Yongqiang Zhou e , Guorong Chen f , Zhe Shen g , Yi Wang c , Guang Liang Deubiquitinase JOSD2 alleviates colitis by inhibiting inflammation via deubiquitination of IMPDH2 in macrophages Acta Pharmaceutica Sinica B, (2024)
Applications
IF
Reactivity
Mouse
Si-Rui Shen 1 2, Zhu-Qi Huang 1 2 3, Yu-Die Yang 1 2, Ji-Bo Han 2 4, Zi-Min Fang 1 2, Yue Guan 1 2, Jia-Chen Xu 1 2, Ju-Lian Min 5, Yi Wang 2, Gao-Jun Wu 1, Zhong-Xiang Xiao 6, Wu Luo 7 8, Zhou-Qing Huang 9, Guang Liang JOSD2 inhibits angiotensin II-induced vascular remodeling by deubiquitinating and stabilizing SMAD7 Acta Pharmacol Sin, (2025)
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