JQAD1

SKU: orb1818805

Description

JQAD1 is a CRBN-dependent PROTAC that selectively targets EP300 for degradation. JQAD1 suppresses EP300 expression and the H3K27ac modification. JQAD1 induces apoptosis. JQAD1 can be used in research of cancer.

Key Properties

• CAS Number: [2417097-18-6]
• MW: 932.954906463623
• Formula: C₄₈H₅₂F₄N₆O₉
• SMILES: O=C1N(C(=O)O[C@]21CCC1=CC(NC(=O)CCCCCCCCCCCNC3=CC=C4C(=O)N(C5CCC(=O)NC5=O)C(=O)C4=C3)=CC=C21)CC(=O)N([C@@H](C)C(F)(F)F)CC1C=CC(F)=CC=1

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only