Kartogenin sodium

SKU: orb2565906

Description

Kartogenin (KGN) sodium acts as an inducer of chondrogenic tissue formation (EC 50: 100 nM). It promotes chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and modulating the CBFβ-RUNX1 transcriptional program. Additionally, Kartogenin sodium aids tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. It is extensively utilized in cell-free therapies for cartilage regeneration and protection, tendon-bone healing, wound healing, and limb development. The compound is also vital for cartilage repair, coordinating limb development, and osteoarthritis (OA) research [1] [2] [3] [4].

Key Properties

• CAS Number: 1401168-39-5
• MW: 339.32
• Purity: 98.00%
• Formula: C₂₀H₁₄NNaO₃
• SMILES: O=C(C1=C(C=CC=C1)C([O-])=O)NC2=CC=C(C3=CC=CC=C3)C=C2.[Na+]

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

140639031