KDM4A (C) Antibody, Rabbit Polyclonal

SKU: orb66988

Description

Rabbit polyclonal to KDM4A.Lysine-specific demethylase 4A (KDM4A) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. KDM4A does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. KDM4A demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono-and dimethylated residues. KDM4A has been shown to participate in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruient of histone deacetylases and NCOR1, respectively.

Research Area

Epigenetics,Product Categories/Products/Antibodies,Infectious Diseases,Product Categories/Products/Antibodies/Primary Antibodies

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:5000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: C-terminal region of human KDM4A
• Molecular Weight: 121
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-KDM4A antibody,anti-Lysinespecific demethylase 4A antibody,anti-JmjC domaincontaining histone demethylation protein 3A antibody,anti-Jumonji domaincontaining protein 2A antibody,anti-JHDM3A antibody,anti-JMJD2 antibody,anti-JMJD2A antibody,anti-KIAA0677 antibody

Quick Database Links

UniProt

O75164